Anatomy · Embryology and Genetics

Karyotyping

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  • Karyotyping: process of arranging the chromosomes of a cell in a standard sequence to study its complete chromosomal complement; the arranged set is the karyotype.

Method

  • An enlarged photomicrograph of a stained metaphase chromosome spread is taken; individual chromosomes are cut out, homologous chromosomes paired, and arranged from longest to shortest.

Denver Classification of Chromosomes

  • Denver system of classification (1960) arranges all chromosomes, including sex chromosomes, into seven groups (A to G), based on size, centromere position, arm length-ratio, and presence of satellite bodies.

Denver classification, chromosome groups