Biochemistry · Clinical Biochemistry and Laboratory Medicine

Adrenal function tests

4 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
Adrenal function tests, 5 to 15 μg/dl at 9.00 AM

Adrenal Gland: Site and Hormone Classes

Objective
Learn the main facts and relationships
Keywords
glucocorticoids, aldosterone, epinephrine

Synthesis of Adrenocorticosteroids

Objective
Follow the sequence and key control points
Keywords
Cholesterol, pregnenolone, cytochrome P450 side chain cleavage enzyme

Mechanism of Action and Regulation

Objective
Track activators, inhibitors and feedback
Keywords
Glucocorticoids, Aldosterone, renin-angiotensin

Metabolism and Assessment of Adrenocortical Function

Objective
Follow the sequence and key control points
Keywords
plasma cortisol, plasma ACTH, urinary 17-ketosteroids

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Addison's disease, Cushing's syndrome, Pheochromocytoma

Definition