← All subjects
MBBS year 1
Biochemistry notes
The whole subject in the order it is taught, 108 topics. Open any one to read it.
Carbohydrate Metabolism
- Glycolysis: pathway, regulation and significance
- TCA cycle: pathway, regulation and significance
- HMP shunt: pathway and significance
- Glycogen metabolism and hormonal regulation
- Glycogen storage diseases
- Gluconeogenesis and its regulation
- Cori cycle
- RBC glycolysis and Rapoport-Luebering cycle
- Integrated regulation of blood glucose
- Glucose transporters
- Pyruvate dehydrogenase complex
Enzymes and Clinical Enzymology
Biomolecules and Proteins
- Protein structure and organization
- Collagen: structure, synthesis and clinical importance
- Plasma proteins and their functions
- Immunoglobulins: structure and functions
- Urea cycle: reactions, regulation and disorders
- Ammonia metabolism, transport and toxicity
- Transamination and deamination
- Phenylalanine and tyrosine metabolism with inborn errors
- Glycine metabolism
- Biologically important peptides
- Biogenic amines
Lipid Metabolism
Heme and Hemoglobin
Bioenergetics
Molecular Biology and Genetics
- DNA structure and organization
- DNA replication
- Transcription
- Translation and protein biosynthesis
- Genetic code and wobble hypothesis
- Gene regulation and lac operon
- Mutation and mutagenesis
- DNA repair mechanisms
- Recombinant DNA technology
- PCR and clinical applications
- Reverse transcription
- RNA types and functions
- Post-transcriptional and post-translational modifications
Nutrition and Metabolic Integration
- Acid-base balance: buffers and physiological regulation
- Metabolic acidosis and compensation
- Water and electrolyte balance
- Balanced diet and principles of nutrition
- Starvation metabolism and metabolic adaptation
- Protein-energy malnutrition
- Kwashiorkor and marasmus
- Integration of carbohydrate, lipid and protein metabolism
- BMR and factors affecting it
- Dietary fibre and health
- Energy requirements and energy balance
- Essential amino acids
- Essential fatty acids
Vitamins and Minerals
- Vitamin A: biochemical functions, deficiency and toxicity
- Vitamin D: metabolism, functions and deficiency
- Vitamin B12 and folate: metabolism and megaloblastic anemia
- Vitamin C: functions and deficiency
- Thiamine: biochemical role and deficiency
- Vitamin B6: biochemical role and deficiency
- Vitamin K: biochemical role and deficiency
- Vitamin E
- Riboflavin and niacin
- Calcium and phosphorus metabolism
- Copper metabolism
- Zinc metabolism and functions
- Magnesium
Clinical Biochemistry and Laboratory Medicine
- Liver function tests and interpretation
- Renal function tests and creatinine clearance
- Thyroid function tests
- Adrenal function tests
- Electrophoresis and clinical applications
- Inborn errors of metabolism: principles and selected examples
- Tumour markers
- Oncogenes and proto-oncogenes
- Detoxification and xenobiotic metabolism
- GAGs and hyaluronic acid
- Chromatography
- Flame photometry
- Radioisotopes in medicine
- Biochemical basis of diabetes mellitus
- Glycosuria and renal threshold for glucose
- HbA1c and its clinical significance
- Plasma proteins and immunoglobulins in clinical disease
- Free radical injury and antioxidant defence
- Metabolic syndrome: biochemical basis
- Hyperuricemia and gout