Biochemistry · Bioenergetics

Oxidative phosphorylation

6 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
Oxidative phosphorylation, complex V, P : O ratio

Site and P : O Ratio

Objective
Learn the main facts and relationships
Keywords
10 H+, 2.5 ATP, 6 H+

Chemiosmotic Hypothesis

Objective
Learn the main facts and relationships
Keywords
Chemiosmotic hypothesis, Chemical coupling hypothesis

ATP Synthase and Rotary Motor Model

Objective
Learn the main facts and relationships
Keywords
ATP synthase, F1, F0

Shuttle Pathways for Reducing Equivalents

Objective
Follow the sequence and key control points
Keywords
Glycerol-phosphate shuttle, Malate-aspartate shuttle

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Cyanide poisoning, Leber's hereditary optic neuropathy, Brown adipose tissue

Definition