Anatomy · Neuroanatomy

Hypothalamus: nuclei, functions and connections

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  • Hypothalamus: small part of diencephalon below the thalamus, forming the floor and lower part of the lateral walls of the third ventricle.
  • Weightabout 4 g (0.3% of brain mass)
  • Controls the autonomic nervous system, endocrine system and limbic system; called the "head ganglion of the autonomic nervous system" (Sherrington).

Subdivisions and Boundaries

  • Anteroposteriorly divided into four regions, each containing its own nuclei: preoptic, supraoptic, tuberal and mammillary.
  • Mediolaterally divided, using the anterior column of fornix as landmark, into a medial zone (periventricular and intermediate sub-zones) and a lateral zone.