Biochemistry · Clinical Biochemistry and Laboratory Medicine

Biochemical basis of diabetes mellitus

6 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
Diabetes mellitus, hyperglycemia, IDDM

Classification of Diabetes Mellitus

Objective
Separate the major categories
Keywords
IDDM (type I), NIDDM (type II), 80 to 90%

Glucose Tolerance Test

Objective
Link tests to interpretation
Keywords
oral glucose tolerance test (OGTT), Glycosuria, renal threshold (180 mg/dl)

Metabolic Changes in Diabetes

Objective
Learn the main facts and relationships
Keywords
hyperglycemia, ketoacidosis, hypertriglyceridemia

Biochemical Indices of Diabetic Control

Objective
Track activators, inhibitors and feedback
Keywords
Glycated hemoglobin (HbA1c), 6 to 8 weeks, 3 to 5%

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Impaired glucose tolerance, 110 to 126 mg/dl, 140 to 200 mg/dl

Definition