Biochemistry · Lipid Metabolism

Fatty acid synthesis

6 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
Fatty acid synthesis, palmitate

Site, Substrates and Pathway Overview

Objective
Follow the sequence and key control points
Keywords
acetyl CoA, NADPH, ATP

Stage I: Acetyl CoA and NADPH Transport to Cytosol

Objective
Learn the main facts and relationships
Keywords
citrate, citrate lyase

Stage III: Fatty Acid Synthase Complex and Synthesis of Palmitate

Objective
Follow the sequence and key control points
Keywords
Fatty acid synthase (FAS), ACP, malonyl CoA

Regulation of Fatty Acid Synthesis

Objective
Follow the sequence and key control points
Keywords
Acetyl CoA carboxylase, Dietary regulation, NADPH availability

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Essential fatty acids, Arachidonic acid, eicosanoids

Definition