Quick Orientation
Section
Definition
- Objective
- Understand the core idea
- Keywords
- Bile pigments, 120-day lifespan, 250 to 350 mg/day
Site and Fate of Erythrocyte Components
- Objective
- Learn the main facts and relationships
- Keywords
- reticuloendothelial (RE) system, globin, heme
Heme Oxygenase and Biliverdin Reductase
- Objective
- Learn the main facts and relationships
- Keywords
- Heme oxygenase, NADPH, O2
Transport of Bilirubin to the Liver
- Objective
- Learn the main facts and relationships
- Keywords
- albumin, 25 mg bilirubin/100 mL plasma, carrier-mediated active transport
Hepatic Conjugation and Biliary Excretion
- Objective
- Learn the main facts and relationships
- Keywords
- two molecules of glucuronate, bilirubin glucuronyltransferase, bilirubin diglucuronide
Clinical Correlation
- Objective
- Connect the mechanism to clinical findings
- Keywords
- Bilirubin-albumin displacement, Urine colour, urobilin