Quick Orientation
Section
Definition
- Objective
- Understand the core idea
- Keywords
- Transamination, transaminases (aminotransferases), Deamination
Transamination Mechanism
- Objective
- Learn the main facts and relationships
- Keywords
- pyridoxal phosphate (PLP), Ping Pong Bi Bi
Role of Glutamate Dehydrogenase
- Objective
- Learn the main facts and relationships
- Keywords
- α-ketoglutarate, glutamate, Glutamate dehydrogenase (GDH)
Amino Acid Oxidases and D-Amino Acids
- Objective
- Learn the main facts and relationships
- Keywords
- L-amino acid oxidase, D-amino acid oxidase, D-amino acids
Clinical Correlation
- Objective
- Connect the mechanism to clinical findings
- Keywords
- Clinical Correlation
Definition
Transamination: transfer of an amino group from an amino acid to a keto acid, interconverting a pair of amino acids and a pair of keto acids, catalysed by transaminases (aminotransferases).