Physiology · Cardiovascular System

Baroreceptor reflex and long-term regulation of blood pressure

4 min read

Definition

  • Baroreceptor reflex (baroreflex, sino-aortic reflex): a rapid neural reflex from carotid sinus and aortic arch stretch receptors that corrects blood pressure within seconds.
  • It is the principal short-term mechanism of BP regulation, operating over 50 to 200 mmHg.

Receptors and Afferent Pathway

  • Baroreceptors are stretch receptors in the carotid sinus and aortic arch wall; a BP rise stimulates them, a fall reduces it.
  • Afferents: glossopharyngeal nerve (IX) from the carotid sinus; vagus nerve (X) from the aortic arch.
  • Baroreceptors are branched, knobby, myelinated terminals and are high-pressure receptors (arterial side).
    • Distinct from low-pressure (cardiopulmonary) baroreceptors in the atria and pulmonary circulation.
  • IX branch (carotid sinus): the carotid sinus nerve (buffer nerve).
  • X branch (aortic arch): the aortic nerve, a distinct branch of vagus only in the rabbit.