Biochemistry · Clinical Biochemistry and Laboratory Medicine

Oncogenes and proto-oncogenes

5 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
Oncogenes, Protooncogenes

Activation of Protooncogenes to Oncogenes

Objective
Learn the main facts and relationships
Keywords
Activation of Protooncogenes to Oncogenes

Mechanism of Action of Oncogenes

Objective
Learn the main facts and relationships
Keywords
oncoproteins, growth factors, growth factor receptors

Growth Factors

Objective
Learn the main facts and relationships
Keywords
Growth Factors

Growth Factor Receptors

Objective
Learn the main facts and relationships
Keywords
Growth Factor Receptors

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Ras-associated cancers, Lung cancer, Psoriasis

Definition

Oncogenes: genes capable of causing cancer (Greek oncos, tumor or mass), originally discovered in tumor-causing viruses.