Biochemistry · Vitamins and Minerals

Vitamin D: metabolism, functions and deficiency

4 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
fat-soluble vitamin, hormone, 9 to 11 mg/dL

Chemistry and Cutaneous Synthesis

Objective
Follow the sequence and key control points
Keywords
7-dehydrocholesterol

Absorption, Transport and Storage

Objective
Learn the main facts and relationships
Keywords
Absorption, Transport and Storage

Synthesis of Calcitriol (Activation Pathway)

Objective
Follow the sequence and key control points
Keywords
25-hydroxycholecalciferol (25-OH D3, calcidiol), 1-hydroxylase

Regulation of 1,25-DHCC Synthesis

Objective
Follow the sequence and key control points
Keywords
1-hydroxylase (kidney), 24-hydroxylase, 24,25-DHCC

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Renal rickets (renal osteodystrophy)

Definition