DNA structure and organization

Definition

Objective

Understand the core idea

Keywords

DNA, 3′,5′-phosphodiester bonds, B-DNA

Structure of DNA

Objective

See how the components fit together

Keywords

3′,5′-phosphodiester bridges, Chargaff's rule, A = T

Conformations of DNA Double Helix

Objective

Learn the main facts and relationships

Keywords

B, A and Z, B-DNA

Unusual DNA Structures

Objective

See how the components fit together

Keywords

Bent DNA, Triple-stranded DNA, T-A-T

Size and Packaging of DNA

Objective

Learn the main facts and relationships

Keywords

kilobase pair (kb) = 10³ bp, megabase pair (Mb) = 10⁶ bp, gigabase pair (Gb) = 10⁹ bp

Clinical Correlation

Objective

Connect the mechanism to clinical findings

Keywords

Cisplatin, Telomeres, G-tetraplexes