Biochemistry · Molecular Biology and Genetics

Transcription

5 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
template (antisense strand), coding (sense) strand, primary transcript

DNA Strands and Selective Transcription

Objective
Learn the main facts and relationships
Keywords
transcription is selective

Transcription in Prokaryotes

Objective
Learn the main facts and relationships
Keywords
DNA-dependent RNA polymerase, promoter region, sigma (σ) factor

Transcription in Eukaryotes

Objective
Learn the main facts and relationships
Keywords
three distinct RNA polymerases, mitochondrial RNA polymerase, Hogness box (TATA box)

Post-transcriptional Modifications

Objective
Learn the main facts and relationships
Keywords
Ribonucleases, tRNA, rRNA

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
β-thalassemia, exon-intron junction, β-globin chain

Definition