Quick Orientation
Section
Definition
- Objective
- Understand the core idea
- Keywords
- Enzyme inhibitor, reversible, irreversible
Reversible Inhibition
- Objective
- Learn the main facts and relationships
- Keywords
- non-covalently, substrate concentration, Succinate dehydrogenase (SDH)
Irreversible Inhibition
- Objective
- Learn the main facts and relationships
- Keywords
- covalently, irreversibly, Iodoacetate
Suicide Inhibition
- Objective
- Learn the main facts and relationships
- Keywords
- same enzyme, irreversibly, Allopurinol
Allosteric Inhibition
- Objective
- Learn the main facts and relationships
- Keywords
- allosteric regulation
Clinical Correlation
- Objective
- Connect the mechanism to clinical findings
- Keywords
- Methanol poisoning, alcohol dehydrogenase (ADH), ethanol
Definition
Enzyme inhibitor: a substance (organic or inorganic) that binds an enzyme and decreases its catalytic activity.