Biochemistry · Enzymes and Clinical Enzymology

Enzyme regulation and clinical significance

6 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
cellular economy

Allosteric Regulation and Allosteric Inhibition

Objective
Track activators, inhibitors and feedback
Keywords
allosteric sites, T, R

Activation of Latent Enzymes

Objective
Learn the main facts and relationships
Keywords
phosphorylation/dephosphorylation, Glycogen phosphorylase, phosphorylase b

Compartmentation

Objective
Learn the main facts and relationships
Keywords
Compartmentation

Control of Enzyme Synthesis

Objective
Follow the sequence and key control points
Keywords
constitutive, adaptive, induction

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
HMG CoA reductase, Isoenzymes

Definition

Enzyme activity is regulated at multiple stages by several mechanisms to achieve cellular economy.