Biochemistry · Carbohydrate Metabolism

Glycolysis: pathway, regulation and significance

6 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
Glycolysis

Tissues Dependent on Anaerobic Glycolysis

Objective
Learn the main facts and relationships
Keywords
Erythrocytes, skeletal muscle, NAD+

Reactions of Glycolysis: Irreversible Steps

Objective
Follow the sequence and key control points
Keywords
hexokinase, phosphofructokinase (PFK), pyruvate kinase

Regulation of Glycolysis

Objective
Track activators, inhibitors and feedback
Keywords
Fructose 2,6-bisphosphate (F2,6-BP), PFK-2, fructose 2,6-bisphosphatase

Production of ATP in Glycolysis

Objective
Learn the main facts and relationships
Keywords
net 2 ATP, 3 ATP, 7 ATP equivalents

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Lactic acidosis, Pasteur effect, phosphofructokinase

Definition