Forensic Medicine · Toxicology — General Principles

Universal Antidote & Ideal Antidote Properties

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Universal Antidote

Definition

A mixture formerly administered in poisoning cases when the nature of the poison was unknown.

Formula (2 : 1 : 1)

ComponentPartsPrinciple of action
Activated charcoal2Adsorbs many poisons
Magnesium oxide1Neutralizes acidic poisons
Tannic acid1Precipitates alkaloids and some toxic substances

Present Status

  • The universal antidote is now largely obsolete.
  • Activated charcoal alone is preferred in modern poisoning management.

Ideal Properties of an Antidote

  • Rapid action
  • Safe and non-toxic
  • Easy administration
  • Specific action against the poison
  • Effective in small dose