Quick Orientation
Section
Definition
- Objective
- Understand the core idea
- Keywords
- Cori cycle
Site of the Cycle
- Objective
- Follow the sequence and key control points
- Keywords
- skeletal muscle, liver
Significance of Lactate Production
- Objective
- Learn the main facts and relationships
- Keywords
- NAD+
Pathway: Lactate to Glucose
- Objective
- Follow the sequence and key control points
- Keywords
- lactate dehydrogenase (LDH), gluconeogenesis, glucose 6-phosphatase
Clinical Correlation
- Objective
- Connect the mechanism to clinical findings
- Keywords
- Clinical Correlation
Definition
Cori cycle: synthesis of glucose in liver from skeletal muscle lactate, and reuse of that glucose by muscle for energy, forming a cycle between the two organs.