Quick Orientation
Section
Definition
- Objective
- Understand the core idea
- Keywords
- DNA repair, double-strand break repair
Major Mechanisms of DNA Repair
- Objective
- Learn the main facts and relationships
- Keywords
- Major Mechanisms of DNA Repair
Base Excision-Repair
- Objective
- Learn the main facts and relationships
- Keywords
- uracil DNA glycosylase, repair DNA polymerase, DNA ligase
Nucleotide Excision-Repair
- Objective
- Learn the main facts and relationships
- Keywords
- UV light, excision nuclease (exinuclease)
Mismatch Repair
- Objective
- Learn the main facts and relationships
- Keywords
- methylated, GATC endonuclease
Clinical Correlation
- Objective
- Connect the mechanism to clinical findings
- Keywords
- Xeroderma pigmentosum (XP), Hereditary nonpolyposis colon cancer (HNPCC)