Biochemistry · Molecular Biology and Genetics

Recombinant DNA technology

8 min read

Quick Orientation

Section

Definition

Objective
Understand the core idea
Keywords
restriction endonucleases, DNA ligase

Molecular Tools of Genetic Engineering

Objective
Learn the main facts and relationships
Keywords
Restriction endonucleases, DNA ligase, EcoRI

Host Cells for Cloning

Objective
Learn the main facts and relationships
Keywords
prokaryotic, eukaryotic

Cloning Vectors

Objective
Learn the main facts and relationships
Keywords
Vectors, plasmid, bacteriophage, cosmid, artificial chromosome

Methods of Gene Transfer

Objective
Learn the main facts and relationships
Keywords
transformation, conjugation, electroporation, lipofection, direct DNA transfer

Clinical Correlation

Objective
Connect the mechanism to clinical findings
Keywords
Post-translational modification, tissue plasminogen activator, Human artificial chromosome (HAC)

Definition